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SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner
Androgen receptor (AR) plays an important regulatory role in prostate cancer. AR's transcriptional activity is regulated by androgenic ligands, but also by post-translational modifications, such as SUMOylation. To study the role of AR SUMOylation in genuine chromatin environment, we compared an...
Autores principales: | Sutinen, Päivi, Malinen, Marjo, Heikkinen, Sami, Palvimo, Jorma J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117771/ https://www.ncbi.nlm.nih.gov/pubmed/24981513 http://dx.doi.org/10.1093/nar/gku543 |
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