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CstF-64 supports pluripotency and regulates cell cycle progression in embryonic stem cells through histone 3′ end processing
Embryonic stem cells (ESCs) exhibit a unique cell cycle with a shortened G(1) phase that supports their pluripotency, while apparently buffering them against pro-differentiation stimuli. In ESCs, expression of replication-dependent histones is a main component of this abbreviated G(1) phase, althoug...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117776/ https://www.ncbi.nlm.nih.gov/pubmed/24957598 http://dx.doi.org/10.1093/nar/gku551 |