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CstF-64 supports pluripotency and regulates cell cycle progression in embryonic stem cells through histone 3′ end processing

Embryonic stem cells (ESCs) exhibit a unique cell cycle with a shortened G(1) phase that supports their pluripotency, while apparently buffering them against pro-differentiation stimuli. In ESCs, expression of replication-dependent histones is a main component of this abbreviated G(1) phase, althoug...

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Detalles Bibliográficos
Autores principales:	Youngblood, Bradford A., Grozdanov, Petar N., MacDonald, Clinton C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117776/ https://www.ncbi.nlm.nih.gov/pubmed/24957598 http://dx.doi.org/10.1093/nar/gku551

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