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Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis

BCL-X mRNA alternative splicing generates pro-apoptotic BCL-XS or anti-apoptotic BCL-XL gene products and the mechanism that regulates splice shifting is incompletely understood. We identified and characterized a long non-coding RNA (lncRNA) named INXS, transcribed from the opposite genomic strand o...

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Detalles Bibliográficos
Autores principales: DeOcesano-Pereira, Carlos, Amaral, Murilo S., Parreira, Kleber S., Ayupe, Ana C., Jacysyn, Jacqueline F., Amarante-Mendes, Gustavo P., Reis, Eduardo M., Verjovski-Almeida, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117780/
https://www.ncbi.nlm.nih.gov/pubmed/24992962
http://dx.doi.org/10.1093/nar/gku561