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Revealing transient structures of nucleosomes as DNA unwinds

The modulation of DNA accessibility by nucleosomes is a fundamental mechanism of gene regulation in eukaryotes. The nucleosome core particle (NCP) consists of 147 bp of DNA wrapped around a symmetric octamer of histone proteins. The dynamics of DNA packaging and unpackaging from the NCP affect all D...

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Detalles Bibliográficos
Autores principales: Chen, Yujie, Tokuda, Joshua M., Topping, Traci, Sutton, Julie L., Meisburger, Steve P., Pabit, Suzette A., Gloss, Lisa M., Pollack, Lois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117781/
https://www.ncbi.nlm.nih.gov/pubmed/24990379
http://dx.doi.org/10.1093/nar/gku562