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DNA topoisomerase VIII: a novel subfamily of type IIB topoisomerases encoded by free or integrated plasmids in Archaea and Bacteria

Type II DNA topoisomerases are divided into two families, IIA and IIB. Types IIA and IIB enzymes share homologous B subunits encompassing the ATP-binding site, but have non-homologous A subunits catalyzing DNA cleavage. Type IIA topoisomerases are ubiquitous in Bacteria and Eukarya, whereas members...

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Detalles Bibliográficos
Autores principales: Gadelle, Danièle, Krupovic, Mart, Raymann, Kasie, Mayer, Claudine, Forterre, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117785/
https://www.ncbi.nlm.nih.gov/pubmed/24990376
http://dx.doi.org/10.1093/nar/gku568