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Reverse gyrase—recent advances and current mechanistic understanding of positive DNA supercoiling

Reverse gyrases are topoisomerases that introduce positive supercoils into DNA in an ATP-dependent reaction. They consist of a helicase domain and a topoisomerase domain that closely cooperate in catalysis. The mechanism of the functional cooperation of these domains has remained elusive. Recent stu...

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Detalles Bibliográficos
Autores principales: Lulchev, Pavel, Klostermeier, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117796/
https://www.ncbi.nlm.nih.gov/pubmed/25013168
http://dx.doi.org/10.1093/nar/gku589