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Reverse gyrase—recent advances and current mechanistic understanding of positive DNA supercoiling
Reverse gyrases are topoisomerases that introduce positive supercoils into DNA in an ATP-dependent reaction. They consist of a helicase domain and a topoisomerase domain that closely cooperate in catalysis. The mechanism of the functional cooperation of these domains has remained elusive. Recent stu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117796/ https://www.ncbi.nlm.nih.gov/pubmed/25013168 http://dx.doi.org/10.1093/nar/gku589 |