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The myeloid binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting

Vascular endothelial cells (ECs) are ideal gene therapy targets as they provide widespread tissue access and are the first contact surfaces following intravenous vector administration. Human recombinant adenovirus serotype 5 (Ad5) is the most frequently used gene transfer system because of its appre...

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Detalles Bibliográficos
Autores principales: Lu, Zhi Hong, Kaliberov, Sergey, Zhang, Jingzhu, Muz, Barbara, Azab, Abdel Kareem, Sohn, Rebecca E., Kaliberova, Lyudmila, Du, Yingqiu, Curiel, David T., Arbeit, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117817/
https://www.ncbi.nlm.nih.gov/pubmed/24955893
http://dx.doi.org/10.1038/labinvest.2014.78