Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

Purpose: Genetic risk assessment is becoming an important component of clinical decision-making. Genetic Risk Scores (GRSs) allow the composite assessment of genetic risk in complex traits. A technically and clinically pertinent question is how to most easily and effectively combine a GRS with an as...

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Detalles Bibliográficos
Autores principales: Goldstein, Benjamin A., Knowles, Joshua W., Salfati, Elias, Ioannidis, John P. A., Assimes, Themistocles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117937/
https://www.ncbi.nlm.nih.gov/pubmed/25136350
http://dx.doi.org/10.3389/fgene.2014.00254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117937/
https://www.ncbi.nlm.nih.gov/pubmed/25136350
http://dx.doi.org/10.3389/fgene.2014.00254

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