A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA

The regulated loading of the replicative helicase minichromosome maintenance proteins 2–7 (MCM2–7) onto replication origins is a prerequisite for replication fork establishment and genomic stability. Origin recognition complex (ORC), Cdc6, and Cdt1 assemble two MCM2–7 hexamers into one double hexame...

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Detalles Bibliográficos
Autores principales: Samel, Stefan A., Fernández-Cid, Alejandra, Sun, Jingchuan, Riera, Alberto, Tognetti, Silvia, Herrera, M. Carmen, Li, Huilin, Speck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117941/
https://www.ncbi.nlm.nih.gov/pubmed/25085418
http://dx.doi.org/10.1101/gad.242404.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117941/
https://www.ncbi.nlm.nih.gov/pubmed/25085418
http://dx.doi.org/10.1101/gad.242404.114

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