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Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells

Inappropriate MET tyrosine kinase receptor signaling is detected in almost all types of human cancer and contributes to malignant growth and MET dependency via proliferative and antiapoptotic activities. Independently, Tensin-4 (TNS4) is emerging as a putative oncogene in many cancer types, but the...

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Detalles Bibliográficos
Autores principales: Muharram, Ghaffar, Sahgal, Pranshu, Korpela, Taina, De Franceschi, Nicola, Kaukonen, Riina, Clark, Katherine, Tulasne, David, Carpén, Olli, Ivaska, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118019/
https://www.ncbi.nlm.nih.gov/pubmed/24814316
http://dx.doi.org/10.1016/j.devcel.2014.03.024