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Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells
Inappropriate MET tyrosine kinase receptor signaling is detected in almost all types of human cancer and contributes to malignant growth and MET dependency via proliferative and antiapoptotic activities. Independently, Tensin-4 (TNS4) is emerging as a putative oncogene in many cancer types, but the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118019/ https://www.ncbi.nlm.nih.gov/pubmed/24814316 http://dx.doi.org/10.1016/j.devcel.2014.03.024 |