Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells

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Inappropriate MET tyrosine kinase receptor signaling is detected in almost all types of human cancer and contributes to malignant growth and MET dependency via proliferative and antiapoptotic activities. Independently, Tensin-4 (TNS4) is emerging as a putative oncogene in many cancer types, but the...

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Detalles Bibliográficos
Autores principales: Muharram, Ghaffar, Sahgal, Pranshu, Korpela, Taina, De Franceschi, Nicola, Kaukonen, Riina, Clark, Katherine, Tulasne, David, Carpén, Olli, Ivaska, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118019/
https://www.ncbi.nlm.nih.gov/pubmed/24814316
http://dx.doi.org/10.1016/j.devcel.2014.03.024

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