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Modulation of Triglyceride and Cholesterol Ester Synthesis Impairs Assembly of Infectious Hepatitis C Virus

In hepatitis C virus infection, replication of the viral genome and virion assembly are linked to cellular metabolic processes. In particular, lipid droplets, which store principally triacylglycerides (TAGs) and cholesterol esters (CEs), have been implicated in production of infectious virus. Here,...

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Detalles Bibliográficos
Autores principales: Liefhebber, Jolanda M. P., Hague, Charlotte V., Zhang, Qifeng, Wakelam, Michael J. O., McLauchlan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118089/
https://www.ncbi.nlm.nih.gov/pubmed/24917668
http://dx.doi.org/10.1074/jbc.M114.582999