Cargando…

Interleukin-6 downregulation with mesenchymal stem cell differentiation results in loss of immunoprivilege

Allogeneic mesenchymal stem cell (MSC) transplantation improves cardiac function, but cellular differentiation results in loss of immunoprivilege and rejection. To explore the mechanism involved in this immune rejection, we investigated the influence of interleukin-6 (IL-6), a factor secreted by MSC...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Peng, Li, Shu-Hong, Wu, Jun, Zang, Wang-Fu, Dhingra, Sanjiv, Sun, Lu, Weisel, Richard D, Li, Ren-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118173/
https://www.ncbi.nlm.nih.gov/pubmed/23802625
http://dx.doi.org/10.1111/jcmm.12092