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Interleukin-6 downregulation with mesenchymal stem cell differentiation results in loss of immunoprivilege
Allogeneic mesenchymal stem cell (MSC) transplantation improves cardiac function, but cellular differentiation results in loss of immunoprivilege and rejection. To explore the mechanism involved in this immune rejection, we investigated the influence of interleukin-6 (IL-6), a factor secreted by MSC...
Autores principales: | Li, Peng, Li, Shu-Hong, Wu, Jun, Zang, Wang-Fu, Dhingra, Sanjiv, Sun, Lu, Weisel, Richard D, Li, Ren-Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118173/ https://www.ncbi.nlm.nih.gov/pubmed/23802625 http://dx.doi.org/10.1111/jcmm.12092 |
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