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Frequent KIT Mutations in Human Gastrointestinal Stromal Tumors

Identifying gene mutations in individual tumors is critical to improve the efficacy of cancer therapy by matching targeted drugs to specific mutations. Gastrointestinal stromal tumors (GIST) are stromal or mesenchymal subepithelial neoplasms affecting the gastrointestinal tract and frequently contai...

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Detalles Bibliográficos
Autores principales: Xu, Zhi, Huo, Xinying, Tang, Chuanning, Ye, Hua, Nandakumar, Vijayalakshmi, Lou, Feng, Zhang, Dandan, Jiang, Shouwen, Sun, Hong, Dong, Haichao, Zhang, Guangchun, Liu, Zhiyuan, Dong, Zhishou, Guo, Baishuai, Yan, He, Yan, Chaowei, Wang, Lu, Su, Ziyi, Li, Yangyang, Gu, Dongying, Zhang, Xiaojing, Wu, Xiaomin, Wei, Xiaowei, Hong, Lingzhi, Zhang, Yangmei, Yang, Jinsong, Gong, Yonglin, Tang, Cuiju, Jones, Lindsey, Huang, Xue F., Chen, Si-Yi, Chen, Jinfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118194/
https://www.ncbi.nlm.nih.gov/pubmed/25080996
http://dx.doi.org/10.1038/srep05907