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Kinetic Hairpin Oligonucleotide Blockers for Selective Amplification of Rare Mutations
Detection of rare mutant alleles in an excess of wild type alleles is increasingly important in cancer diagnosis. Several methods for selective amplification of a mutant allele via the polymerase chain reaction (PCR) have been reported, but each of these methods has its own limitations. A common pro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118197/ https://www.ncbi.nlm.nih.gov/pubmed/25082368 http://dx.doi.org/10.1038/srep05921 |