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Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats
Alzheimer's disease (AD) and cerebral ischaemia share similar features in terms of altered amyloid precursor protein (APP) processing and β-amyloid (Aβ) accumulation. We have previously shown that Aβ and calcium deposition, and β-secretase activity, are robustly increased in the ipsilateral tha...
Autores principales: | Sarajärvi, Timo, Lipsanen, Anu, Mäkinen, Petra, Peräniemi, Sirpa, Soininen, Hilkka, Haapasalo, Annakaisa, Jolkkonen, Jukka, Hiltunen, Mikko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118244/ https://www.ncbi.nlm.nih.gov/pubmed/22805236 http://dx.doi.org/10.1111/j.1582-4934.2012.01599.x |
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