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Topical application of phosphatidyl-inositol-3,5-bisphosphate for acute lung injury in neonatal swine
Hypoxemic respiratory failure of the neonatal organism involves increased acid sphingomyelinase (aSMase) activity and production of ceramide, a second messenger of a pro-inflammatory pathway that promotes increased vascular permeability, surfactant alterations and alveolar epithelial apoptosis. We c...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118249/ https://www.ncbi.nlm.nih.gov/pubmed/22882773 http://dx.doi.org/10.1111/j.1582-4934.2012.01618.x |