Cargando…

BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks

Replication fork stalling can promote genomic instability, predisposing to cancer and other diseases(1–3). Stalled replication forks may be processed by sister chromatid recombination (SCR), generating error-free or error-prone homologous recombination (HR) outcomes(4–8). In mammalian cells, a long-...

Descripción completa

Detalles Bibliográficos
Autores principales: Willis, Nicholas A., Chandramouly, Gurushankar, Huang, Bin, Kwok, Amy, Follonier, Cindy, Deng, Chuxia, Scully, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118467/
https://www.ncbi.nlm.nih.gov/pubmed/24776801
http://dx.doi.org/10.1038/nature13295