Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment

BACKGROUND: KIR genes coding for natural killer cell immunoglobulin-like receptors, KIR, influence the effector and regulatory function of NK cells as well as some subpopulations of T lymphocytes (e.g. CD4+CD28-KIR+) depending on presence of ligands (particularly HLA-C molecules). KIR-KIR ligand int...

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Detalles Bibliográficos
Autores principales: Majorczyk, Edyta, Pawlik, Andrzej, Gendosz, Daria, Kuśnierczyk, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118653/
https://www.ncbi.nlm.nih.gov/pubmed/25069714
http://dx.doi.org/10.1186/1471-2474-15-256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118653/
https://www.ncbi.nlm.nih.gov/pubmed/25069714
http://dx.doi.org/10.1186/1471-2474-15-256

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