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Crystallization and preliminary crystallographic study of human coronavirus NL63 main protease in complex with an inhibitor

Human coronavirus NL63 mainly infects younger children and causes cough, fever, rhinorrhoea, bronchiolitis and croup. It encodes two polyprotein precursors required for genome replication and transcription. Each polyprotein undergoes extensive proteolytic processing, resulting in functional subunits...

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Detalles Bibliográficos
Autores principales: Wang, Fenghua, Tan, Yusheng, Li, Huiyan, Chen, Xia, Wang, Jinshan, Li, Shuang, Fu, Sheng, Zhao, Qi, Chen, Cheng, Su, Dan, Yang, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118806/
https://www.ncbi.nlm.nih.gov/pubmed/25084384
http://dx.doi.org/10.1107/S2053230X14012953