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Crystallization and preliminary crystallographic study of human coronavirus NL63 main protease in complex with an inhibitor
Human coronavirus NL63 mainly infects younger children and causes cough, fever, rhinorrhoea, bronchiolitis and croup. It encodes two polyprotein precursors required for genome replication and transcription. Each polyprotein undergoes extensive proteolytic processing, resulting in functional subunits...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118806/ https://www.ncbi.nlm.nih.gov/pubmed/25084384 http://dx.doi.org/10.1107/S2053230X14012953 |