A Fluorescent Protein Scaffold for Presenting Structurally Constrained Peptides Provides an Effective Screening System to Identify High Affinity Target-Binding Peptides

Peptides that have high affinity for target molecules on the surface of cancer cells are crucial for the development of targeted cancer therapies. However, unstructured peptides often fail to bind their target molecules with high affinity. To efficiently identify high-affinity target-binding peptide...

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Detalles Bibliográficos
Autores principales: Kadonosono, Tetsuya, Yabe, Etsuri, Furuta, Tadaomi, Yamano, Akihiro, Tsubaki, Takuya, Sekine, Takuya, Kuchimaru, Takahiro, Sakurai, Minoru, Kizaka-Kondoh, Shinae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118881/
https://www.ncbi.nlm.nih.gov/pubmed/25084350
http://dx.doi.org/10.1371/journal.pone.0103397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118881/
https://www.ncbi.nlm.nih.gov/pubmed/25084350
http://dx.doi.org/10.1371/journal.pone.0103397

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