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Chikungunya Virus Exploits miR-146a to Regulate NF-κB Pathway in Human Synovial Fibroblasts

OBJECTIVES: Chikungunya virus causes chronic infection with manifestations of joint pain. Human synovial fibroblasts get infected with CHIKV and could lead to pro-inflammatory responses. MicroRNAs have potentials to regulate the gene expression of various anti-viral and pro-inflammatory genes. The s...

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Detalles Bibliográficos
Autores principales: Selvamani, Sakthi Priya, Mishra, Ritu, Singh, Sunit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118904/
https://www.ncbi.nlm.nih.gov/pubmed/25083878
http://dx.doi.org/10.1371/journal.pone.0103624