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Structural Insights into Calcium-Bound S100P and the V Domain of the RAGE Complex

The S100P protein is a member of the S100 family of calcium-binding proteins and possesses both intracellular and extracellular functions. Extracellular S100P binds to the cell surface receptor for advanced glycation end products (RAGE) and activates its downstream signaling cascade to meditate tumo...

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Detalles Bibliográficos
Autores principales: Penumutchu, Srinivasa R., Chou, Ruey-Hwang, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118983/
https://www.ncbi.nlm.nih.gov/pubmed/25084534
http://dx.doi.org/10.1371/journal.pone.0103947