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Structural Insights into Calcium-Bound S100P and the V Domain of the RAGE Complex
The S100P protein is a member of the S100 family of calcium-binding proteins and possesses both intracellular and extracellular functions. Extracellular S100P binds to the cell surface receptor for advanced glycation end products (RAGE) and activates its downstream signaling cascade to meditate tumo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118983/ https://www.ncbi.nlm.nih.gov/pubmed/25084534 http://dx.doi.org/10.1371/journal.pone.0103947 |