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Rictor Is Required for Early B Cell Development in Bone Marrow

The development of early B cells, which are generated from hematopoietic stem cells (HSCs) in a series of well-characterized stages in bone marrow (BM), represents a paradigm for terminal differentiation processes. Akt is primarily regulated by phosphorylation at Thr308 by PDK1 and at Ser473 by mTOR...

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Detalles Bibliográficos
Autores principales: Zhang, Yingchi, Hu, Tianyuan, Hua, Chunlan, Gu, Jie, Zhang, Liyan, Hao, Sha, Liang, Haoyue, Wang, Xiaomin, Wang, Weili, Xu, Jing, Liu, Hanzhi, Liu, Bin, Cheng, Tao, Yuan, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119011/
https://www.ncbi.nlm.nih.gov/pubmed/25084011
http://dx.doi.org/10.1371/journal.pone.0103970