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In silico single strand melting curve: a new approach to identify nucleic acid polymorphisms in Totiviridae

BACKGROUND: The PCR technique and its variations have been increasingly used in the clinical laboratory and recent advances in this field generated new higher resolution techniques based on nucleic acid denaturation dynamics. The principle of these new molecular tools is based on the comparison of m...

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Detalles Bibliográficos
Autores principales: Oliveira, Raffael AC, Almeida, Ricardo VM, Dantas, Márcia DA, Castro, Felipe N, Lima, João Paulo MS, Lanza, Daniel CF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119202/
https://www.ncbi.nlm.nih.gov/pubmed/25030031
http://dx.doi.org/10.1186/1471-2105-15-243