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In silico single strand melting curve: a new approach to identify nucleic acid polymorphisms in Totiviridae
BACKGROUND: The PCR technique and its variations have been increasingly used in the clinical laboratory and recent advances in this field generated new higher resolution techniques based on nucleic acid denaturation dynamics. The principle of these new molecular tools is based on the comparison of m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119202/ https://www.ncbi.nlm.nih.gov/pubmed/25030031 http://dx.doi.org/10.1186/1471-2105-15-243 |