APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions

Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage caused by endogenous and exogenous agents. APE1 acts as a reductive activator of many transcription factors (TFs) and has also been named re...

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Detalles Bibliográficos
Autores principales: Thakur, Shweta, Sarkar, Bibekananda, Cholia, Ravi P, Gautam, Nandini, Dhiman, Monisha, Mantha, Anil K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119211/
https://www.ncbi.nlm.nih.gov/pubmed/25033834
http://dx.doi.org/10.1038/emm.2014.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119211/
https://www.ncbi.nlm.nih.gov/pubmed/25033834
http://dx.doi.org/10.1038/emm.2014.42

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