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MiR-17-5p modulates osteoblastic differentiation and cell proliferation by targeting SMAD7 in non-traumatic osteonecrosis

MicroRNAs (miRNAs) have recently been recognized to have a role in human orthopedic disorders. The objective of our study was to explore the expression profile and biological function of miRNA-17-5p (miR-17-5p), which is well known to be related to cancer cell proliferation and invasion, in osteobla...

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Detalles Bibliográficos
Autores principales: Jia, Jie, Feng, Xiaobo, Xu, Weihua, Yang, Shuhua, Zhang, Qing, Liu, Xianzhe, Feng, Yong, Dai, Zhipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119212/
https://www.ncbi.nlm.nih.gov/pubmed/25060766
http://dx.doi.org/10.1038/emm.2014.43