ERK1/2/COX-2/PGE(2) signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes

PURPOSE: Retinal vascular dysfunction caused by vascular endothelial growth factor (VEGF) is the major pathological change that occurs in diabetic retinopathy (DR). It has recently been demonstrated that G protein-coupled receptor 91 (GPR91) plays a major role in both vasculature development and ret...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Hu, Jianyan, Du, Shanshan, Chen, Yongdong, Wang, Shuai, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119234/
https://www.ncbi.nlm.nih.gov/pubmed/25324681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119234/
https://www.ncbi.nlm.nih.gov/pubmed/25324681

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