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Studying the organization of DNA repair by single-cell and single-molecule imaging

DNA repair safeguards the genome against a diversity of DNA damaging agents. Although the mechanisms of many repair proteins have been examined separately in vitro, far less is known about the coordinated function of the whole repair machinery in vivo. Furthermore, single-cell studies indicate that...

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Detalles Bibliográficos
Autores principales: Uphoff, Stephan, Kapanidis, Achillefs N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119245/
https://www.ncbi.nlm.nih.gov/pubmed/24629485
http://dx.doi.org/10.1016/j.dnarep.2014.02.015