A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12

The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in vitro assays do not fully predict metastatic behavior, and the majority of studies have used cloned cell lines, which do not reflect primary tumor hetero...

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Detalles Bibliográficos
Autores principales: Duquet, Arnaud, Melotti, Alice, Mishra, Sonakshi, Malerba, Monica, Seth, Chandan, Conod, Arwen, Ruiz i Altaba, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119353/
https://www.ncbi.nlm.nih.gov/pubmed/24920608
http://dx.doi.org/10.15252/emmm.201303799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119353/
https://www.ncbi.nlm.nih.gov/pubmed/24920608
http://dx.doi.org/10.15252/emmm.201303799

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