Beta-lapachone inhibits pathological retinal neovascularization in oxygen-induced retinopathy via regulation of HIF-1α

Retinal neovascularization in retinopathy of prematurity (ROP) is the most common cause of blindness for children. Despite evidence that hypoxia inducible factor (HIF)-1α -VEGF axis is associated with the pathogenesis of ROP, the inhibitors of HIF-1α have not been established as a therapeutic target...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Sung Wook, Kim, Jin Hyoung, Kim, Ko-Eun, Jeong, Moon Hee, Park, Hyunsung, Park, Bongju, Suh, Young-Ger, Park, Woo Jin, Kim, Jeong Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119393/
https://www.ncbi.nlm.nih.gov/pubmed/24533641
http://dx.doi.org/10.1111/jcmm.12235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119393/
https://www.ncbi.nlm.nih.gov/pubmed/24533641
http://dx.doi.org/10.1111/jcmm.12235

Ejemplares similares