Cargando…

Beta-lapachone inhibits pathological retinal neovascularization in oxygen-induced retinopathy via regulation of HIF-1α

Retinal neovascularization in retinopathy of prematurity (ROP) is the most common cause of blindness for children. Despite evidence that hypoxia inducible factor (HIF)-1α -VEGF axis is associated with the pathogenesis of ROP, the inhibitors of HIF-1α have not been established as a therapeutic target...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Sung Wook, Kim, Jin Hyoung, Kim, Ko-Eun, Jeong, Moon Hee, Park, Hyunsung, Park, Bongju, Suh, Young-Ger, Park, Woo Jin, Kim, Jeong Hun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119393/ https://www.ncbi.nlm.nih.gov/pubmed/24533641 http://dx.doi.org/10.1111/jcmm.12235

Ejemplares similares

Hypoxic repression of CYP7A1 through a HIF-1α- and SHP-independent mechanism
por: Moon, Yunwon, et al.
Publicado: (2016)

Impact of Micellar Vehicles on in situ Intestinal Absorption Properties of Beta-Lapachone in Rats
por: Jang, Soung Baek, et al.
Publicado: (2013)

Beta-Lapachone, a Modulator of NAD Metabolism, Prevents Health Declines in Aged Mice
por: Lee, Jeong-sook, et al.
Publicado: (2012)

Deguelin inhibits retinal neovascularization by down-regulation of HIF-1α in oxygen-induced retinopathy
por: Kim, J H, et al.
Publicado: (2008)

β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia
por: Lee, Eun-Jung, et al.
Publicado: (2015)

RAGE mediated intracellular Aβ uptake contributes to the breakdown of tight junction in retinal pigment epithelium
por: Park, Sung Wook, et al.
Publicado: (2015)

Inhibition of choroidal neovascularization by homoisoflavanone, a new angiogenesis inhibitor
por: Kim, Jeong Hun, et al.
Publicado: (2008)

Relationship between Pericytes and Endothelial Cells in Retinal Neovascularization: A Histological and Immunofluorescent Study of Retinal Angiogenesis
por: Choi, Se Hyun, et al.
Publicado: (2018)

β-Lapachone Ameliorates Lipotoxic Cardiomyopathy in Acyl CoA Synthase Transgenic Mice
por: Jeong, Moon Hee, et al.
Publicado: (2014)

Decursin inhibits retinal neovascularization via suppression of VEGFR-2 activation
por: Kim, Jeong Hun, et al.
Publicado: (2009)

β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway
por: Kee, Ji-Ye, et al.
Publicado: (2017)

Inhibitory effect of Samul-tang on retinal neovascularization in oxygen-induced retinopathy
por: Lee, Yun Mi, et al.
Publicado: (2015)

CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration
por: Koo, Taeyoung, et al.
Publicado: (2018)

Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway
por: Park, Wonjin, et al.
Publicado: (2019)

Peripheral Retinal Neovascularization with Vitreous Hemorrhage in HIV Retinopathy
por: Jiramongkolchai, Kim, et al.
Publicado: (2017)

β-Lapachone Significantly Increases the Effect of Ionizing Radiation to Cause Mitochondrial Apoptosis via JNK Activation in Cancer Cells
por: Park, Moon-Taek, et al.
Publicado: (2011)

Relationships among Retinal Nonperfusion, Neovascularization, and Vascular Endothelial Growth Factor Levels in Quiescent Proliferative Diabetic Retinopathy
por: Ra, Ho, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress-Induced JNK Activation Is a Critical Event Leading to Mitochondria-Mediated Cell Death Caused by β-Lapachone Treatment
por: Lee, Hyemi, et al.
Publicado: (2011)

β-Lapachone Inhibits Lung Metastasis of Colorectal Cancer by Inducing Apoptosis of CT26 Cells
por: Kee, Ji-Ye, et al.
Publicado: (2016)

The matricellular protein CCN5 inhibits fibrotic deformation of retinal pigment epithelium
por: Yoon, Aeri, et al.
Publicado: (2018)

Enhancement of radiation effect using beta-lapachone and underlying mechanism
por: Ahn, Ki Jung, et al.
Publicado: (2013)

Aucuba japonica extract inhibits retinal neovascularization in a mouse model of oxygen‐induced retinopathy, with its bioactive components preventing VEGF‐induced retinal vascular hyperpermeability
por: Jung, Eunsoo, et al.
Publicado: (2020)

Intravenously Administered Anti-recoverin Antibody Alone Does Not Pass through the Blood-Retinal Barrier
por: Kim, Jeong Hun, et al.
Publicado: (2011)

Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson’s Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways
por: Park, Jin-Sun, et al.
Publicado: (2019)

Novel Dioxygenases, HIF-α Specific Prolyl-hydroxylase and Asparanginyl-hydroxylase: O(2) Switch for Cell Survival
por: Park, Hyunsung
Publicado: (2008)

A Case of Syphilitic Outer Retinitis Mimicking Acute Zonal Occult Outer Retinopathy
por: Kim, Jeong Ah, et al.
Publicado: (2014)

Sulodexide inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy
por: Jo, Hyoung, et al.
Publicado: (2014)

Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis
por: Park, Bongju, et al.
Publicado: (2019)

Human Apolipoprotein(a) Kringle V Inhibits Ischemia-Induced Retinal Neovascularization via Suppression of Fibronectin-Mediated Angiogenesis
por: Lim, Yangmi, et al.
Publicado: (2012)

Effect of Guibi-Tang, a Traditional Herbal Formula, on Retinal Neovascularization in a Mouse Model of Proliferative Retinopathy
por: Lee, Yun Mi, et al.
Publicado: (2015)

Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice
por: Im, Sora, et al.
Publicado: (2022)

Increased Expression and Activity of 12-Lipoxygenase in Oxygen-Induced Ischemic Retinopathy and Proliferative Diabetic Retinopathy: Implications in Retinal Neovascularization
por: Al-Shabrawey, Mohamed, et al.
Publicado: (2011)

YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity
por: Lee, Gwan-Jun, et al.
Publicado: (2022)

Correction: Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice
por: Im, Sora, et al.
Publicado: (2023)

Amelioration of Huntington's disease phenotypes by Beta-Lapachone is associated with increases in Sirt1 expression, CREB phosphorylation and PGC-1α deacetylation
por: Lee, Mijung, et al.
Publicado: (2018)

Animal models of diabetic retinopathy: doors to investigate pathogenesis and potential therapeutics
por: Jo, Dong Hyun, et al.
Publicado: (2013)

Association of statin use and hypertriglyceridemia with diabetic macular edema in patients with type 2 diabetes and diabetic retinopathy
por: Chung, Yoo-Ri, et al.
Publicado: (2017)

Diabetic retinopathy is associated with diastolic dysfunction in type 2 diabetic patients with non-ischemic dilated cardiomyopathy
por: Chung, Yoo-Ri, et al.
Publicado: (2017)

NQO1 is Required for β-Lapachone-Mediated Downregulation of Breast-Cancer Stem-Cell Activity
por: Kim, Dong Wook, et al.
Publicado: (2018)

Cedilanid inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy
por: Zhang, Jing Shang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_702smntrpkms40js91bbnb44k9