Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

Mutations in the vacuolar protein sorting 35 homolog (VPS35) gene at the PARK17 locus, encoding a key component of the retromer complex, were recently identified as a new cause of late-onset, autosomal dominant Parkinson's disease (PD). Here we explore the pathogenic consequences of PD-associat...

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Detalles Bibliográficos
Autores principales: Tsika, Elpida, Glauser, Liliane, Moser, Roger, Fiser, Aris, Daniel, Guillaume, Sheerin, Una-Marie, Lees, Andrew, Troncoso, Juan C., Lewis, Patrick A., Bandopadhyay, Rina, Schneider, Bernard L., Moore, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119414/
https://www.ncbi.nlm.nih.gov/pubmed/24740878
http://dx.doi.org/10.1093/hmg/ddu178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119414/
https://www.ncbi.nlm.nih.gov/pubmed/24740878
http://dx.doi.org/10.1093/hmg/ddu178

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