The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis

ORCTL3 is a member of a group of genes, the so-called anticancer genes, that cause tumour-specific cell death. We show that this activity is triggered in isogenic renal cells upon their transformation independently of the cells’ proliferation status. For its cell death effect ORCTL3 targets the enzy...

Descripción completa

Detalles Bibliográficos
Autores principales: AbuAli, G, Chaisaklert, W, Stelloo, E, Pazarentzos, E, Hwang, M-S, Qize, D, Harding, SV, Al-Rubaish, A, Alzahrani, A-H, Al-Ali, A, Sanders, TAB, Aboagye, E O, Grimm, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119473/
https://www.ncbi.nlm.nih.gov/pubmed/24769897
http://dx.doi.org/10.1038/onc.2014.93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119473/
https://www.ncbi.nlm.nih.gov/pubmed/24769897
http://dx.doi.org/10.1038/onc.2014.93

Ejemplares similares