The p85 Regulatory Subunit of PI3K Mediates cAMP-PKA and Insulin Biological Effects on MCF-7 Cell Growth and Motility

Recent studies have shown that hyperinsulinemia may increase the cancer risk. Moreover, many tumors demonstrate an increased activation of IR signaling pathways. Phosphatidylinositol 3-kinase (PI3K) is necessary for insulin action. In epithelial cells, which do not express GLUT4 and gluconeogenic en...

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Detalles Bibliográficos
Autores principales: Di Zazzo, E., Feola, A., Zuchegna, C., Romano, A., Donini, C. F., Bartollino, S., Costagliola, C., Frunzio, R., Laccetti, P., Di Domenico, M., Porcellini, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119716/
https://www.ncbi.nlm.nih.gov/pubmed/25114970
http://dx.doi.org/10.1155/2014/565839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119716/
https://www.ncbi.nlm.nih.gov/pubmed/25114970
http://dx.doi.org/10.1155/2014/565839

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