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Amplification of the Insulin-Like Growth Factor 1 Receptor Gene Is a Rare Event in Adrenocortical Adenocarcinomas: Searching for Potential Mechanisms of Overexpression

Context. IGF1R overexpression appears to be a prognostic biomarker of metastatic pediatric adrenocortical tumors. However, the molecular mechanisms that are implicated in its upregulation remain unknown. Aim. To investigate the potential mechanisms involved in IGF1R overexpression. Patients and Meth...

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Detalles Bibliográficos
Autores principales: Ribeiro, Tamaya Castro, Jorge, Alexander Augusto, Almeida, Madson Q., Mariani, Beatriz Marinho de Paula, Nishi, Mirian Yumi, Mendonca, Berenice Bilharinho, Fragoso, Maria Candida Barisson Villares, Latronico, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119736/
https://www.ncbi.nlm.nih.gov/pubmed/25110710
http://dx.doi.org/10.1155/2014/936031