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Effect of Duplicate Genes on Mouse Genetic Robustness: An Update

In contrast to S. cerevisiae and C. elegans, analyses based on the current knockout (KO) mouse phenotypes led to the conclusion that duplicate genes had almost no role in mouse genetic robustness. It has been suggested that the bias of mouse KO database toward ancient duplicates may possibly cause t...

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Detalles Bibliográficos
Autores principales: Su, Zhixi, Wang, Junqiang, Gu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119742/
https://www.ncbi.nlm.nih.gov/pubmed/25110693
http://dx.doi.org/10.1155/2014/758672