Asymmetric Fluorination of α-Branched Cyclohexanones Enabled by a Combination of Chiral Anion Phase-Transfer Catalysis and Enamine Catalysis using Protected Amino Acids

[Image: see text] We report a study involving the successful merger of two separate chiral catalytic cycles: a chiral anion phase-transfer catalysis cycle to activate Selectfluor and an enamine activation cycle, using a protected amino acid as organocatalyst. We have demonstrated the viability of th...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyu, Phipps, Robert J., Toste, F. Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119784/
https://www.ncbi.nlm.nih.gov/pubmed/24684209
http://dx.doi.org/10.1021/ja500882x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119784/
https://www.ncbi.nlm.nih.gov/pubmed/24684209
http://dx.doi.org/10.1021/ja500882x

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