miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110

The miR-34/449 family consists of six homologous miRNAs at three genomic loci. Redundancy of miR-34/449 miRNAs and their dominant expression in multiciliated epithelia suggest a functional significance in ciliogenesis. Here, we report that mice deficient for all miR-34/449 miRNAs exhibited postnatal...

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Detalles Bibliográficos
Autores principales: Song, Rui, Walentek, Peter, Sponer, Nicole, Klimke, Alexander, Lee, Joon Sub, Dixon, Gary, Harland, Richard, Wan, Ying, Lishko, Polina, Lize, Muriel, Kessel, Michael, He, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119886/
https://www.ncbi.nlm.nih.gov/pubmed/24899310
http://dx.doi.org/10.1038/nature13413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119886/
https://www.ncbi.nlm.nih.gov/pubmed/24899310
http://dx.doi.org/10.1038/nature13413

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