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Epigenetic Silencing of CXCR4 Promotes Loss of Cell Adhesion in Cervical Cancer

In the network of chemokine signaling pathways, recent reports have described the SDF-1α/CXCR4 axis and its role in cancer progression and metastasis. Interestingly, we found downregulation of CXCR4 at both transcript and protein level in cervical cancer cell lines and primary tumors. We also found...

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Detalles Bibliográficos
Autores principales: Yadav, Suresh Singh, Prasad, Shyam Babu, Das, Mitali, Kumari, Soni, Pandey, Lakshmi Kant, Singh, Sunita, Pradhan, Satyajit, Narayan, Gopeshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119908/
https://www.ncbi.nlm.nih.gov/pubmed/25114911
http://dx.doi.org/10.1155/2014/581403