Novel role of pancreatic differentiation 2 in facilitating self-renewal and drug resistance of pancreatic cancer stem cells

BACKGROUND: Cancer stem cells (CSCs) contribute towards disease aggressiveness and drug resistance. Specific identification of CSC maintenance genes and targeting can improve the efficiency of currently available treatment modalities. Pancreatic differentiation 2 (PD2) has a major role in the self-r...

Descripción completa

Detalles Bibliográficos
Autores principales: Vaz, A P, Ponnusamy, M P, Rachagani, S, Dey, P, Ganti, A K, Batra, S K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119968/
https://www.ncbi.nlm.nih.gov/pubmed/25003666
http://dx.doi.org/10.1038/bjc.2014.152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119968/
https://www.ncbi.nlm.nih.gov/pubmed/25003666
http://dx.doi.org/10.1038/bjc.2014.152

Ejemplares similares