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Similar blood-borne DNA methylation alterations in cancer and inflammatory diseases determined by subpopulation shifts in peripheral leukocytes

BACKGROUND: Although many DNA methylation (DNAm) alterations observed in peripheral whole blood/leukocytes and serum have been considered as potential diagnostic markers for cancer, their origin and their specificity for cancer (e.g., vs inflammatory diseases) remain unclear. METHODS: From publicly...

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Detalles Bibliográficos
Autores principales: Li, H, Zheng, T, Chen, B, Hong, G, Zhang, W, Shi, T, Li, S, Ao, L, Wang, C, Guo, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119994/
https://www.ncbi.nlm.nih.gov/pubmed/24960404
http://dx.doi.org/10.1038/bjc.2014.347