Kinetic Interpretation of the Importance of OATP1B3 and MRP2 in Docetaxel-Induced Hematopoietic Toxicity

Neutropenia is a lethal dose-limiting toxicity of docetaxel. Our previous report indicated that the prevalence of severe docetaxel-induced neutropenia is significantly associated with genetic polymorphisms in solute carrier organic anion transporter 1B3 (SLCO1B3) (encoding organic anion–transporting...

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Detalles Bibliográficos
Autores principales: Yamada, A, Maeda, K, Kiyotani, K, Mushiroda, T, Nakamura, Y, Sugiyama, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120017/
https://www.ncbi.nlm.nih.gov/pubmed/25054314
http://dx.doi.org/10.1038/psp.2014.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120017/
https://www.ncbi.nlm.nih.gov/pubmed/25054314
http://dx.doi.org/10.1038/psp.2014.23

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