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Vascular histone deacetylation by pharmacological HDAC inhibition

HDAC inhibitors can regulate gene expression by post-translational modification of histone as well as nonhistone proteins. Often studied at single loci, increased histone acetylation is the paradigmatic mechanism of action. However, little is known of the extent of genome-wide changes in cells stimu...

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Detalles Bibliográficos
Autores principales: Rafehi, Haloom, Balcerczyk, Aneta, Lunke, Sebastian, Kaspi, Antony, Ziemann, Mark, KN, Harikrishnan, Okabe, Jun, Khurana, Ishant, Ooi, Jenny, Khan, Abdul Waheed, Du, Xiao-Jun, Chang, Lisa, Haviv, Izhak, Keating, Samuel T., Karagiannis, Tom C., El-Osta, Assam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120081/
https://www.ncbi.nlm.nih.gov/pubmed/24732587
http://dx.doi.org/10.1101/gr.168781.113