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Computational prediction of hinge axes in proteins

BACKGROUND: A protein's function is determined by the wide range of motions exhibited by its 3D structure. However, current experimental techniques are not able to reliably provide the level of detail required for elucidating the exact mechanisms of protein motion essential for effective drug s...

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Detalles Bibliográficos
Autores principales: Shamsuddin, Rittika, Doktorova, Milka, Jaswal, Sheila, Lee-St John, Audrey, McMenimen, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120148/
https://www.ncbi.nlm.nih.gov/pubmed/25080829
http://dx.doi.org/10.1186/1471-2105-15-S8-S2