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Computational prediction of hinge axes in proteins
BACKGROUND: A protein's function is determined by the wide range of motions exhibited by its 3D structure. However, current experimental techniques are not able to reliably provide the level of detail required for elucidating the exact mechanisms of protein motion essential for effective drug s...
Autores principales: | Shamsuddin, Rittika, Doktorova, Milka, Jaswal, Sheila, Lee-St John, Audrey, McMenimen, Kathryn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120148/ https://www.ncbi.nlm.nih.gov/pubmed/25080829 http://dx.doi.org/10.1186/1471-2105-15-S8-S2 |
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