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Exploring representations of protein structure for automated remote homology detection and mapping of protein structure space

BACKGROUND: Due to rapid sequencing of genomes, there are now millions of deposited protein sequences with no known function. Fast sequence-based comparisons allow detecting close homologs for a protein of interest to transfer functional information from the homologs to the given protein. Sequence-b...

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Detalles Bibliográficos
Autores principales: Molloy, Kevin, Van, M Jennifer, Barbara, Daniel, Shehu, Amarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120149/
https://www.ncbi.nlm.nih.gov/pubmed/25080993
http://dx.doi.org/10.1186/1471-2105-15-S8-S4