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Recombinant human activated protein C for the treatment of severe sepsis and septic shock: a study protocol for incorporating observational evidence using a Bayesian approach

INTRODUCTION: Activated protein C (aPC) plays a pivotal role in modulating a severe inflammatory response and is thought to be beneficial for patients with sepsis. However, several meta-analyses of randomised controlled trials (RCTs) show that aPC is not significantly associated with improved surviv...

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Detalles Bibliográficos
Autor principal: Zhang, Zhongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120342/
https://www.ncbi.nlm.nih.gov/pubmed/25082420
http://dx.doi.org/10.1136/bmjopen-2014-005622